Only VF spaceships are immune to the massive environment (and probably not all of them, check their store description), but you exchange your firepower limit for the safety from environmental hazards. As a counter measure you get more satellites slots on these.
Müllers are generally considered to be the most universal spacecrafts for any kind of mission, except M408. Nobody seems to like M408. They have the +20 extra firepower level that helps, kind of.
Then there are BX bombers which are always slow, but they have way more fire power than any other type of a ship. Also they are quite huge, so are their collision circles, so it’s not as trivial to dodge when using them as with other spacecrafts.
As for heat sinks, reactors, engines and basically everything else, if you have patience, fuel and keys, go for the best ones with legendary rarity (three 
icons next to the name). Otherwise simply look at the values in the store:
